Meconium Aspiration Syndrome: The Core Concept of Pathophysiology during Resuscitation

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Meconium Aspiration Syndrome – The Core Concept of Pathophysiology during Resuscitation

Aspiration of meconium produces a syndrome (Meconium Aspiration Syndrome MAS) characterized by hypoxia, hypercapnia, and acidosis. Perinatal hypoxia, acute airway obstruction, pulmonary inflammation, pulmonary vasoconstriction, pulm­ onary hypertension, and surfactant inactivation all play a role in the pathogenesis of MAS. Most aspiration of meconium probably occurs before birth. Following asp...

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Newborn Resuscitation: Meconium Aspiration Syndrome

At present time, delivery room management of babies born through Meconium stained amniotic fluid (MSAF) often includes suctioning of the mouth and nose before the delivery of the shoulders. This addresses the concern that babies will inhale meconium present in the upper airway with their first breath putting them at risk of MAS. The rationale of routine perineal suctioning of all babies born th...

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Meconium aspiration syndrome: pathophysiology and prevention.

BACKGROUND Despite the common occurrence of intrauterine meconium passage and resultant meconium aspiration syndrome (MAS), controversies regarding the pathophysiology and use of appropriate preventive strategies abound. METHODS Databases from MEDLINE, MD Consult, and the Science Citation Index were searched from 1964 to the present to find relevant sources of information. RESULTS AND CONCL...

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Meconium aspiration syndrome in neonates

Perhaps the most significant changes in airway management over the recent years have been in the management of an infant delivered through meconium- stained amniotic fluid( MSAF). MSAF occurs in approximately 10℅ to 20℅ of all deliveries and increases to over 30℅ in deliveries after 42 weeks gestation. Meconium aspiration syndrome ( MAS) occurs in about 2℅ to 5℅ of these cases with a high morta...

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Meconium aspiration syndrome.

In the years 1977-82, 43 infants with the meconium aspiration syndrome (MAS) were managed at the Department of Paediatrics of Turku University Central Hospital (TUCH), Finland. Among 5,353 deliveries in one year the incidence of meconium staining was 8.7%. By extrapolation, the incidence of meconium aspiration in all newborns is approximately 0.13%. The mean duration of the pregnancies was 39.2...

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ژورنال

عنوان ژورنال: Neonatal Medicine

سال: 2017

ISSN: 2287-9412,2287-9803

DOI: 10.5385/nm.2017.24.2.53